Genetic and Systemic Disease States
Genetic and Systemic Disease States

Genetic and Systemic Disease States

Source: Saylor

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A question pack on advanced pathobiology from Saylor Academy.

This content is licensed under the Creative Commons Attribution 3.0 Unported License.

Genetic and Systemic Disease States Q1

The structural unit of skeletal muscle from Z line to Z line is known as ______________.

A

actin

B

myosin

C

a sarcomere

D

a fascicle

Genetic and Systemic Disease States Q2

The tube that drains urine from the bladder out of the body is known as the ______________.

A

ureter

B

urethra

C

Loop of Henle

D

glomerulus

Genetic and Systemic Disease States Q3

How do the endocrine and nervous system differ?

A

The endocrine system has fast signaling, while the nervous system does not.

B

The endocrine system has long lasting effects, while the nervous system does not.

C

The nervous system has slow signaling, while the endocrine system does not.

D

The nervous system has long lasting effects, while the endocrine system does not.

Genetic and Systemic Disease States Q4

If a dog breeder is trying to determine if his female dog is HH or Hh for having the gene to hear, what dog should she breed her dog with to determine this?

A

A male dog that can hear (HH or Hh)

B

A male dog that is deaf (hh)

C

A male dog that has hearing difficulties (HH or Hh or possibly hh)

D

A male dog that is known to be HH

Genetic and Systemic Disease States Q5

If a man with brown eyes (brown is dominant) is BB and has children with a woman who has blue eyes bb, what are the possible phenotypes of their children?

A

brown only

B

blue only

C

blue and brown

D

green

Genetic and Systemic Disease States Q6

The skin is involved in which of the following?

A

Temperature regulation

B

Sensory reception

C

Protection

D

All of the above

Genetic and Systemic Disease States Q7

What is the main difference between rheumatoid arthritis (RA) and osteoarthritis (OA)?

A

There is pain in the joints in OA, not in RA.

B

RA is an autoimmune disorder, while OA is not.

C

There is swelling of joints in RA, not in OA.

D

OA causes inflammation of the joints, while RA does not.

Genetic and Systemic Disease States Q8

What is the main role of the endocrine system?

A

To maintain homeostasis

B

To prevent spread of disease

C

To protection of body's organs

D

To transmit rapid signaling

Genetic and Systemic Disease States Q9

What is the primary goal of the Human Genome Project?

A

To show what gene does what

B

To show how all genes interact with one another

C

To show all of the genetic material on a living thing's chromosome

D

To show what genes cause what diseases

Genetic and Systemic Disease States Q10

What is the protein absent in Duchenne Muscular Dystrophy (DMD) called?

A

Actin

B

Myosin

C

Dystrophin

D

Sarcoglycan

Genetic and Systemic Disease States Q11

What lab test is most sensitive and specific for myocardial infarction?

A

Blood CK-MB

B

Blood glucose

C

Urine blood

D

Blood calcium

Genetic and Systemic Disease States Q12

What part of the brain is initially impacted by Alzheimer's disease?

A

Thalamus

B

Diencephalon

C

Hippocampus

D

Cerebral cortex

Genetic and Systemic Disease States Q13

What part of the neuron is responsible for bringing the signal into the cell?

A

Soma

B

Dendrite

C

Axon

D

Myelin

Genetic and Systemic Disease States Q14

When a plaque ruptures prior to myocardial infarction, it results in which of the following?

A

Decreased blood flow to the brain

B

Thrombus formation

C

Development in the coronary veins

D

Circulation throughout the body

Genetic and Systemic Disease States Q15

Where do the faulty genes come from in children with cystic fibrosis?

A

The mother only

B

The father only

C

The mother and the father

D

Neither the mother nor the father

Genetic and Systemic Disease States Q16

Which muscle type is voluntary?

A

Cardiac

B

Smooth

C

Skeletal

D

Both A and C

Genetic and Systemic Disease States Q17

Which of the following about bone density is true?

A

It increases with age.

B

There is only one technique to estimate it.

C

A T score of -2 is indicative of osteoporosis.

D

T scores are based on standard deviations.

Genetic and Systemic Disease States Q18

Which of the following about gene mutations is true?

A

They always lead to disease.

B

They usually occur in young cells.

C

If found in cells other than egg and sperm, they can still be passed to offspring.

D

They are often repaired by themselves.

Genetic and Systemic Disease States Q19

Which of the following about Syphilis is true?

A

It has no cure.

B

It has two phases—early and late.

C

It cannot be passed from mother to baby.

D

It begins with the formation of a chancre sore.

Genetic and Systemic Disease States Q20

Which of the following about Syphilis is true?

A

It is caused by the virus Treponema pallidum.

B

It is transmitted by casual contact with infected persons.

C

The best test to diagnose it will depend on what stage it is in.

D

It should not be treated using penicillin.

Genetic and Systemic Disease States Q21

Which of the following about the kidney is true?

A

It filters urine.

B

It does not produce hormones.

C

It regulates plasma volume.

D

It does not regulate electrolytes levels.

Genetic and Systemic Disease States Q22

Which of the following can occur with atherosclerosis?

A

Angina

B

Mini-strokes

C

Transient ischemic attacks

D

All of the above

Genetic and Systemic Disease States Q23

Which of the following demographics is at greatest risk for hip fracture as they age?

A

Caucasian women

B

Caucasian men

C

African-American women

D

African-American men

Genetic and Systemic Disease States Q24

Which of the following DOES NOT contribute to atherosclerosis?

A

HDL

B

LDL

C

Smoking

D

High blood pressure

Genetic and Systemic Disease States Q25

Which of the following DOES NOT make up the circulatory system?

A

Pectoral girdle

B

Quadriceps

C

Pelvic girdle

D

Diaphragm

E

Heart

F

Arteries

G

Veins

H

Lymph nodes

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